Tuberculosis http://kplu.org en UW Team Hunts Tiny Genetic Flaws Linked to Big Problems http://kplu.org/post/uw-team-hunts-tiny-genetic-flaws-linked-big-problems <p><span style="line-height: 1.5;">Even the tiniest misprint in a person’s genetic code can cause big health problems, but they can be hard to find. Now members of a team at University of Washington say they’ve designed </span><a href="http://www.nature.com/nchem/journal/vaop/ncurrent/abs/nchem.1713.html" style="line-height: 1.5;" target="_blank">a better way to track down those mutations.</a></p><p>If you think of DNA as a twisted ladder, each rung is made of two little structures called bases, stuck together. If even one of the billions of these rungs gets copied wrong it can have serious consequences, such as which kind of tuberculosis you get.</p><p> Wed, 31 Jul 2013 05:10:29 +0000 Gabriel Spitzer 9475 at http://kplu.org UW Team Hunts Tiny Genetic Flaws Linked to Big Problems A dozen cases of tuberculosis that resists all drugs found in India http://kplu.org/post/dozen-cases-tuberculosis-resists-all-drugs-found-india Tuberculosis specialists in India <a href="http://cid.oxfordjournals.org/content/early/2011/11/24/cid.cir889.extract?sid=28c0e5de-cca5-4f3d-96eb-414bc0cb7294">have diagnosed</a> infections in a dozen patients in Mumbai that are unfazed by the three first-choice TB drugs and all nine second-line drugs.<p>The doctors are calling them "totally drug-resistant TB," and the infections are essentially incurable with all available medicines.<p>It's a sobering development. Wed, 11 Jan 2012 18:39:14 +0000 Richard Knox 3677 at http://kplu.org A dozen cases of tuberculosis that resists all drugs found in India Global tuberculosis cases drop for first time http://kplu.org/post/global-tuberculosis-cases-drop-first-time Worldwide tuberculosis cases are declining annually for the first time, according to a <a href="http://www.who.int/tb/publications/global_report/en/index.html">report</a> just out from the World Health Organization. Deaths from the disease have also sunk to the lowest level in a decade.<p>The number of people who fell ill with <a href="http://www.who.int/features/qa/08/en/index.html">TB</a> in 2010 dropped to 8.8 million after peaking at 9 million in 2005, WHO says. The number of TB deaths fell to 1.4 million after peaking at 1.8 million in 2003. Tue, 11 Oct 2011 20:40:30 +0000 2874 at http://kplu.org Global tuberculosis cases drop for first time One of every three of us on planet has TB; Seattle rates remain twice national average http://kplu.org/post/one-every-three-us-planet-has-tb-seattle-rates-remain-twice-national-average <p>My friends always tend to disbelieve me (in general, but also specifically) when I tell them that one out of every three people on the planet has been infected with tuberculosis.</p><p>So where are all these consumptive folks, they might say? &mdash; This is assuming they know that TB used to be called consumption because of the way it &ldquo;consumed&rdquo; and withered the body as the infection progressed.</p><p style="margin-top: 0px; margin-right: 0px; margin-bottom: 15px; margin-left: 0px; padding-top: 0px; padding-right: 0px; padding-bottom: 0px; padding-left: 0px; border-top-width: 0px; border-right-width: 0px; border-bottom-width: 0px; border-left-width: 0px; border-style: initial; border-color: initial; outline-width: 0px; outline-style: initial; outline-color: initial; font-size: 14px; vertical-align: baseline; background-image: initial; background-attachment: initial; background-origin: initial; background-clip: initial; background-color: transparent; background-position: initial initial; background-repeat: initial initial; ">They&rsquo;re everywhere, I&rsquo;d reply, including right here in wealthy and smug Seattle.</p><p style="margin-top: 0px; margin-right: 0px; margin-bottom: 15px; margin-left: 0px; padding-top: 0px; padding-right: 0px; padding-bottom: 0px; padding-left: 0px; border-top-width: 0px; border-right-width: 0px; border-bottom-width: 0px; border-left-width: 0px; border-style: initial; border-color: initial; outline-width: 0px; outline-style: initial; outline-color: initial; font-size: 14px; vertical-align: baseline; background-image: initial; background-attachment: initial; background-origin: initial; background-clip: initial; background-color: transparent; background-position: initial initial; background-repeat: initial initial; "><a href="http://www.seattlepi.com/local/429985_tuberculosis10.html" style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; padding-top: 0px; padding-right: 0px; padding-bottom: 0px; padding-left: 0px; font-size: 14px; vertical-align: baseline; background-image: initial; background-attachment: initial; background-origin: initial; background-clip: initial; background-color: transparent; color: rgb(51, 102, 204); text-decoration: none; font-weight: bold; background-position: initial initial; background-repeat: initial initial; " target="_blank">Seattle, in fact, has one of the worst problems with TB in the nation</a>. But it&rsquo;s always here, managed by the public health folks, so it&rsquo;s hardly news.</p><p style="margin-top: 0px; margin-right: 0px; margin-bottom: 15px; margin-left: 0px; padding-top: 0px; padding-right: 0px; padding-bottom: 0px; padding-left: 0px; border-top-width: 0px; border-right-width: 0px; border-bottom-width: 0px; border-left-width: 0px; border-style: initial; border-color: initial; outline-width: 0px; outline-style: initial; outline-color: initial; font-size: 14px; vertical-align: baseline; background-image: initial; background-attachment: initial; background-origin: initial; background-clip: initial; background-color: transparent; background-position: initial initial; background-repeat: initial initial; ">The news <em>is</em> that it&rsquo;s World TB Day.</p><p><a href="http://humanosphere.kplu.org/2011/03/one-out-of-every-three-of-us-have-tb/">Read More</a></p><p> Thu, 24 Mar 2011 18:19:10 +0000 Tom Paulson 1067 at http://kplu.org One of every three of us on planet has TB; Seattle rates remain twice national average