DNA

Science
10:10 pm
Tue July 30, 2013

UW Team Hunts Tiny Genetic Flaws Linked to Big Problems

A rendering shows how synthetic DNA bonds with real DNA, revealing the presence of a flaw.
Courtesy of University of Washington / Nature Chemistry

Even the tiniest misprint in a person’s genetic code can cause big health problems, but they can be hard to find. Now members of a team at University of Washington say they’ve designed a better way to track down those mutations.

If you think of DNA as a twisted ladder, each rung is made of two little structures called bases, stuck together. If even one of the billions of these rungs gets copied wrong it can have serious consequences, such as which kind of tuberculosis you get.

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Law
9:45 am
Thu June 13, 2013

Natural DNA Cannot Be Patented, Supreme Court Rules

Originally published on Thu June 13, 2013 8:28 am

In a decision that could have broad-reaching effects on the future of science and medicine, the Supreme Court ruled Thursday that:

-- "A naturally occurring DNA segment is a product of nature and not patent eligible merely because it has been isolated."

-- But, synthetically created "strands of nucleotides known as composite DNA (cDNA)" are "patent eligible" because they do not occur naturally.

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Science
6:29 pm
Wed September 5, 2012

Seattle team has big role in Human Genome 2.0

DNA molecule unwinding from inside the nucleus of a cell.
NHGRI

It's not officially called Human Genome 2.0. But, key scientists say the research results published Wednesday should re-kindle some of the promise of the Human Genome Project.

One of those key scientists is John Stamatoyannopoloulos of the University of Washington, along with his team of about 40 researchers.

"One of the important hopes here is that this will reinvigorate drug development that’s built around the genome," he says.

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Microbes among us
3:51 pm
Fri February 3, 2012

Tech innovation unveils Puget Sound's secret natural recyclers

This graphical map shows how millions of strands of DNA form a tangle of information, from bacteria, archaea, and viruses -- and helps show which ones can be grouped together.
Vaughn Iverson UW

Scientists have deciphered some of the secrets of one of Puget Sound’s natural recyclers. It’s a microbe – which likes to eat sulfur and nitrogen – and might be found near any of our beaches.  

The technique they devised could open the door to a better understanding of microbial life that abounds everywhere – in the oceans, in soils, and in the human body.

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